Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.64 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.63 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.61 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.61 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.61 |
| ▸ | NSD2 | O96028 | 2/20 | 0.61 |
| ▸ | PCMT1 | P22061 | 2/20 | 0.61 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.61 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.61 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.61 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.61 |
| ▸ | RNMT | O43148 | 1/20 | 0.61 |
| ▸ | INMT | O95050 | 1/20 | 0.61 |
| ▸ | TPMT | P51580 | 1/20 | 0.61 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.61 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.61 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.61 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.61 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.61 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400828 | 1.00 | NNMT (0.64) | NNMTPRMT1DOT1LPRMT7DNMT3B | |
| SCHEMBL27514667 | 0.91 | NNMT (0.64) | NNMTPRMT1DOT1LPRMT7DNMT3B | |
| SCHEMBL29378634 | 0.91 | NNMT (0.64) | NNMTPRMT1DOT1LPRMT7DNMT3B | |
| SCHEMBL9754 | 0.91 | NNMT (0.64) | NNMTPRMT1DOT1LPRMT7DNMT3B | |
| SCHEMBL22444816 | 0.91 | NNMT (0.64) | NNMTPRMT1DOT1LPRMT7DNMT3B | |
| Hydrogen Sulfide SCHEMBL27973834 | 0.90 | NNMT (0.62) | NNMTPRMT1DOT1LPRMT7DNMT3B | |
| SCHEMBL28380075 | 0.89 | DOT1L (0.64) | NNMTPRMT1DOT1LPRMT7DNMT3B | |
| SCHEMBL3636881 | 0.89 | DOT1L (0.64) | NNMTPRMT1DOT1LPRMT7DNMT3B | |
| SCHEMBL28961195 | 0.89 | DOT1L (0.67) | NNMTPRMT1DOT1LPRMT7DNMT3B | |
| SCHEMBL29827630 | 0.88 | DOT1L (0.62) | NNMTPRMT1DOT1LPRMT7DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11766412-B2 | Methods of treating or alleviating adenylosuccinatelyase (ADSL) deficiency using spermidine or a pharmaceutically acceptable salt of spermidine | GENEHEAL BIOTECHNOLOGY CO., LTD. (CN) | 2023-09-26 | — | — | US | disclosed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11766412-B2 | Methods of treating or alleviating adenylosuccinatelyase (ADSL) deficiency using spermidine or a pharmaceutically acceptable salt of spermidine | ADSL, ADSS2, SRM | NNMT 472/4885PRMT1 1329/4885DOT1L 1938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.