Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.38 |
| ▸ | PROC | P04070 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222812 | 1.00 | ALOX5 (0.43) | ALOX5NAMPTGRIN3BGRIN1GRIN2C | |
| SCHEMBL2916499 | 0.83 | CA2 (0.54) | ALOX5NAMPTGRIN3BGRIN1GRIN2C | |
| SCHEMBL6221023 | 0.83 | ALOX5 (0.40) | ALOX5NAMPTGRIN3BGRIN1GRIN2C | |
| SCHEMBL8128914 | 0.79 | POLB (0.41) | ALOX5NAMPTGRIN3BGRIN1GRIN2C | |
| SCHEMBL6219931 | 0.72 | CYP2A6 (0.51) | NAMPTF10PRSS1CA2COMT | |
| SCHEMBL4710724 | 0.72 | ALOX5 (0.44) | ALOX5NAMPTGRIN3BGRIN1GRIN2C | |
| SCHEMBL5262440 | 0.71 | AKR1B1 (0.67) | — | |
| SCHEMBL28017683 | 0.71 | ALOX5 (0.43) | ALOX5NAMPTGRIN3BGRIN1GRIN2C | |
| SCHEMBL4474940 | 0.71 | F10 (0.40) | F10PLATPROCPRSS1F2 | |
| SCHEMBL329450 | 0.71 | CA2 (0.67) | CA2LOXL2CA12CA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |