SCHEMBL2994318

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2994921	0.90	EGFR (0.42)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL2997041	0.90	MAPK1 (0.44)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL2991919	0.90	MAPK1 (0.39)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL5238339	0.85	MAPK1 (0.42)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL2994319	0.83	MAPK1 (0.44)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL2996624	0.83	MAPK1 (0.44)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL2988730	0.82	MAPK1 (0.43)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL424159	0.81	GRIN1 (0.46)	GRIN1GRIN2BKDM4EALDH1A1HPGD
	SCHEMBL2997172	0.81	RAB9A (0.38)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL2995703	0.80	ALDH1A1 (0.38)	MAPK1EGFRTYMSLTA4HVDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.