SCHEMBL2996624

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2988730	0.92	MAPK1 (0.43)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL2997041	0.91	MAPK1 (0.44)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL424159	0.91	GRIN1 (0.46)	GRIN2BFKBP1AALDH1A1HPGDUSP2
	SCHEMBL4878856	0.91	GRIN2B (0.38)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL2995703	0.90	ALDH1A1 (0.38)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL4872850	0.89	BRD4 (0.39)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL5234725	0.87	EGFR (0.42)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL2997172	0.86	RAB9A (0.38)	MAPK1EGFRTYMSLTA4HVDR
	SCHEMBL2996596	0.86	MAPT (0.40)	EGFRGRIN2BALDH1A1HPGDBRD4
	SCHEMBL2990438	0.86	LMNA (0.38)	MAPK1EGFRTYMSLTA4HVDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.