Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KMO | O15229 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.47 |
| ▸ | DHFR | P00374 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630485 | 1.00 | ALDH1A1 (0.55) | ALDH1A1HPGDMEN1GAAKMT2A | |
| SCHEMBL23630487 | 0.86 | NPC1 (0.54) | ALDH1A1HPGDMEN1GAAKMT2A | |
| SCHEMBL29943975 | 0.86 | NPC1 (0.54) | ALDH1A1HPGDMEN1GAAKMT2A | |
| SCHEMBL23630405 | 0.80 | PIK3CA (0.54) | ALDH1A1GAAKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL29943886 | 0.80 | PIK3CA (0.54) | ALDH1A1GAAKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL23630324 | 0.77 | SMO (0.45) | ALDH1A1MEN1GAAKMT2AKDM4E | |
| SCHEMBL23630521 | 0.77 | PRKCQ (0.40) | ALDH1A1HPGDMEN1GAAKMT2A | |
| SCHEMBL32688379 | 0.75 | ALDH1A1 (0.80) | ALDH1A1HPGDMEN1GAAKMT2A | |
| SCHEMBL26154653 | 0.74 | ALDH1A1 (0.60) | ALDH1A1HPGDMEN1GAAKMT2A | |
| SCHEMBL23630386 | 0.73 | KDM4E (0.36) | ALDH1A1GAAKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087658-A1 | SMARCA2-VHL DEGRADERS | Amgen Inc. (US) | 2022-11-16 | — | — | EP | disclosed |