Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | F13A1 | P00488 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | TGM1 | P22735 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14283239 | 0.79 | ALDH1A1 (0.70) | USP2ALDH1A1HSD17B10PKMPOLB | |
| SCHEMBL12455096 | 0.79 | USP2 (0.68) | USP2ALDH1A1HSD17B10PKMPOLB | |
| SCHEMBL4655481 | 0.77 | USP2 (0.71) | USP2ALDH1A1HSD17B10POLBMEN1 | |
| SCHEMBL4655484 | 0.77 | USP2 (0.71) | USP2ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL6945990 | 0.77 | USP2 (0.71) | USP2ALDH1A1HSD17B10POLBMEN1 | |
| SCHEMBL436674 | 0.76 | PKM (0.89) | USP2ALDH1A1HSD17B10PKMPOLB | |
| SCHEMBL13982817 | 0.75 | ALDH1A1 (0.65) | USP2ALDH1A1HSD17B10PKMPOLB | |
| SCHEMBL13982806 | 0.75 | USP2 (0.67) | USP2ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL31527639 | 0.75 | USP2 (0.67) | USP2ALDH1A1HSD17B10POLBMEN1 | |
| SCHEMBL27183343 | 0.75 | ALDH1A1 (0.69) | USP2ALDH1A1HSD17B10PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518960-B2 | Antiviral drugs for treatment or prevention of dengue infection | SIGA TECHNOLOGIES, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | SIGA TECHNOLOGIES, INC. | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | EIF2AK2, HAVCR2, SNRPE | USP2 3743/4885ALDH1A1 2072/4885HSD17B10 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.