SCHEMBL2994439

SCHEMBL2994439

O=S(=O)(F)C(F)(F)Sc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
HSD11B1 P28845 2/20 0.37
FAAH O00519 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
ELANE P08246 1/20 0.35
PRTN3 P24158 1/20 0.35
PRSS3 P35030 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MGLL Q99685 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA13 Q8N1Q1 1/20 0.34
PTPN1 P18031 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5017164 0.81 PTPN1 (0.40) CA1CA2CA5ACA9HSD11B1
SCHEMBL2992202 0.79 CA1 (0.35) CA1CA2CA5ACA9HSD11B1
Lithium Ion SCHEMBL5015182 0.79 GPR3 (0.39) CA1CA2CA5ACA9HSD11B1
SCHEMBL13266199 0.75 PTGS1 (0.44) CA1CA2CA5ACA9SMN1; SMN2
Lithium SCHEMBL2991326 0.74 PTGS1 (0.43) CA1CA2CA5ACA9SMN1; SMN2
SCHEMBL2988178 0.71 CA2 (0.50) CA1CA2CA9MAPTCA12
SCHEMBL777056 0.71 ALDH1A1 (0.56) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL5013864 0.69 PTPN1 (0.38) CA1CA2CA5ACA9HSD11B1
SCHEMBL431548 0.69 MAPT (0.43) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL9338259 0.69 SMN1; SMN2 (0.43) MAPTHPGDSMN1; SMN2MGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084166-B1 PREPARATION PROCESS OF AROMATIC SULFONYLIMIDES INST NAT POLYTECHNIQUE DE GRENOBLE (FR) 2017-11-22 EP disclosed
US-8853448-B2 Aromatic sulfonylimides, preparation thereof and use thereof as electrolyte INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) 2014-10-07 US disclosed
US-8853448-B2 Aromatic sulfonylimides, preparation thereof and use thereof as electrolyte INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) 2014-10-07 US disclosed
US-8853448-B2 Aromatic sulfonylimides, preparation thereof and use thereof as electrolyte INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) 2014-10-07 US disclosed
US-20100174113-A1 AROMATIC SULPHONYLIMIDES, PREPARATION THEREOF AND USE THEREOF AS ELECTROLYTE INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) 2010-07-08 US disclosed
US-20100174113-A1 AROMATIC SULPHONYLIMIDES, PREPARATION THEREOF AND USE THEREOF AS ELECTROLYTE INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) 2010-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100174113-A1 AROMATIC SULPHONYLIMIDES, PREPARATION THEREOF AND USE THEREOF AS ELECTROLYTE AFF2, ARSA, FGFR2 CA1 1507/4885CA2 173/4885CA5A 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.