Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.55 |
| ▸ | BTK | Q06187 | 19/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29944802 | 0.94 | JAK3 (0.56) | JAK3BTKEGFR | |
| SCHEMBL29773396 | 0.83 | JAK3 (0.72) | JAK3BTKEGFR | |
| SCHEMBL29944809 | 0.82 | ENPP2 (0.37) | JAK3 | |
| SCHEMBL29527874 | 0.76 | JAK3 (0.63) | JAK3BTKEGFR | |
| SCHEMBL29944807 | 0.76 | JAK3 (0.56) | JAK3BTKEGFR | |
| SCHEMBL29944772 | 0.76 | ENPP2 (0.39) | JAK3 | |
| SCHEMBL22609896 | 0.72 | JAK3 (0.84) | JAK3BTKEGFR | |
| SCHEMBL22496765 | 0.71 | JAK3 (1.00) | JAK3BTKEGFR | |
| SCHEMBL22496758 | 0.71 | JAK3 (1.00) | JAK3BTKEGFR | |
| SCHEMBL22441068 | 0.70 | JAK3 (1.00) | JAK3BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244055-B | Pyrimidine five-membered ring derivative and application thereof | 江苏先声药业有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-115244055-A | Pyrimido five-membered ring derivative and application thereof | 江苏先声药业有限公司 | 2022-10-25 | — | — | CN | disclosed |