Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.31 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744180 | 0.80 | HTR2A (0.39) | GPR3HTR2A | |
| SCHEMBL8416742 | 0.79 | GPR3 (0.50) | GPR3TNKS2PBRM1HTR2CHTR2A | |
| SCHEMBL29945705 | 0.79 | GPR3 (0.50) | GPR3TNKS2PBRM1HTR2CHTR2A | |
| SCHEMBL215606 | 0.79 | LMNA (0.39) | GPR3HTR2AHTR2BALDH1A1LMNA | |
| SCHEMBL6424856 | 0.74 | HTR2A (0.38) | GPR3HTR2AHTR2B | |
| SCHEMBL7708874 | 0.74 | SLC6A2 (0.30) | — | |
| SCHEMBL4634572 | 0.74 | GPR3 (0.38) | GPR3HTR2AHTR2BSLC22A2SLC22A3 | |
| SCHEMBL3701444 | 0.74 | HTR2A (0.40) | GPR3HTR2A | |
| SCHEMBL5356093 | 0.73 | SLC6A2 (0.31) | — | |
| SCHEMBL8744967 | 0.72 | GPR3 (0.34) | GPR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627440-B1 | Metallocenes containing 9-substituted fluorenyl compounds and use of the metallocenes | PHILLIPS PETROLEUM CO (US) | 1999-08-18 | — | — | EP | disclosed |
| US-5610247-A | Unbridged metallocenes of 9-substituted fluorenyl compounds and use thereof | PHILLIPS PETROLEUM COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0627440-A1 | 9-Substituted fluorenyl compounds and the preparation and use of metallocenes thereof | PHILLIPS PETROLEUM COMPANY (US) | 1994-12-07 | — | — | EP | disclosed |