Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526090 | 0.79 | PDE5A (0.38) | PDE3BPDE3AGAALMNAKMT2A | |
| SCHEMBL29945835 | 0.79 | PDE5A (0.38) | PDE3BPDE3AGAALMNAKMT2A | |
| SCHEMBL4767274 | 0.79 | ABCC8 (0.48) | KMT2AKDM4EMAPTABCC8KCNJ11 | |
| SCHEMBL30493129 | 0.74 | KDM4E (0.42) | PDE3AGAALMNAGLAPOLB | |
| SCHEMBL30014008 | 0.71 | ALDH1A1 (0.50) | PDE3BPDE3AGAAKDM4ESOS1 | |
| SCHEMBL29945961 | 0.70 | POLB (0.37) | PDE3BPDE3AGAALMNAGLA | |
| SCHEMBL30493112 | 0.70 | SMN1; SMN2 (0.45) | GAALMNAGLAPOLBSMARCA2 | |
| SCHEMBL16235200 | 0.69 | KDM4E (0.37) | LMNAKMT2AKDM4EPDE10AMITF | |
| SCHEMBL30014143 | 0.68 | KDM4E (0.62) | GAALMNAPOLBKDM4EMAPT | |
| SCHEMBL23525876 | 0.67 | PDE3A (0.46) | PDE3BPDE3AKDM4EPDE10AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462626-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115135315-B | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |