Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | CTSE | P14091 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15950964 | 0.87 | GPR119 (0.50) | GPR119PTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL25432161 | 0.86 | NR1H2 (0.40) | GPR119PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL27459322 | 0.86 | GPR119 (0.47) | GPR119PTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL1582522 | 0.86 | GPR119 (0.47) | GPR119PTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL1557907 | 0.86 | CTSD (0.49) | GPR119PTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL3131511 | 0.86 | GPR119 (0.47) | GPR119PTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL31273679 | 0.85 | GPR119 (0.46) | GPR119PTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL29098488 | 0.85 | GPR119 (0.46) | GPR119PTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL20046185 | 0.85 | GPR119 (0.49) | GPR119PTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL14637172 | 0.84 | STS (0.46) | GPR119PTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |