Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946030 | 0.85 | MEN1 (0.41) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL29945963 | 0.81 | GPR119 (0.49) | MAPTGPR119 | |
| SCHEMBL29946004 | 0.77 | CTSB (0.39) | MAPTCTSBKDM1AMPOHSD11B1 | |
| SCHEMBL25145660 | 0.69 | SLC6A4 (0.49) | KDM1ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL24266549 | 0.68 | HTR6 (0.41) | KDM1AGPR119SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29946071 | 0.67 | ALK (0.49) | KDM1AGPR119SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8514152 | 0.67 | GPR119 (0.69) | KDM1AGPR119SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24265686 | 0.67 | KDM1A (0.44) | KDM1AGPR119SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29574126 | 0.67 | KDM1A (0.44) | KDM1AGPR119SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12487383 | 0.67 | MEN1 (0.58) | MEN1ALDH1A1MAPTPKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |