Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946016 | 0.87 | GPR119 (0.46) | GPR119TP53 | |
| SCHEMBL24265551 | 0.87 | STS (0.48) | GPR119JAK2YAP1PRMT5 | |
| SCHEMBL29945914 | 0.87 | GPR119 (0.44) | GPR119IRAK4EGLN2 | |
| SCHEMBL29945930 | 0.86 | GPR119 (0.54) | GPR119TP53 | |
| SCHEMBL24265672 | 0.86 | GPR119 (0.49) | GPR119IRAK4 | |
| SCHEMBL29574130 | 0.86 | GPR119 (0.49) | GPR119IRAK4 | |
| SCHEMBL14636005 | 0.82 | GPR119 (0.50) | GPR119TP53 | |
| SCHEMBL29945968 | 0.81 | GPR119 (0.44) | GPR119 | |
| SCHEMBL29946078 | 0.80 | GPR119 (0.49) | GPR119EGLN2 | |
| SCHEMBL29945954 | 0.79 | KDM1A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |