Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.44 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.44 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.44 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.44 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.44 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.44 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24265551 | 0.90 | STS (0.48) | GPR119STSSMN1; SMN2GAA | |
| SCHEMBL29945930 | 0.89 | GPR119 (0.54) | GPR119TP53 | |
| SCHEMBL29945962 | 0.87 | GPR119 (0.53) | GPR119TP53 | |
| SCHEMBL29946022 | 0.87 | NR3C1 (0.44) | GPR119NR3C1STSTP53CACNB4 | |
| SCHEMBL29945877 | 0.85 | GPR119 (0.43) | GPR119NR3C1STSTP53CACNB4 | |
| SCHEMBL14636005 | 0.84 | GPR119 (0.50) | GPR119TP53MEN1KMT2ANPSR1 | |
| SCHEMBL29945968 | 0.83 | GPR119 (0.44) | GPR119NR3C1STSCACNB4CACNA1A | |
| SCHEMBL29945914 | 0.80 | GPR119 (0.44) | GPR119 | |
| SCHEMBL29946041 | 0.79 | GPR119 (0.45) | GPR119TP53SMN1; SMN2LMNA | |
| SCHEMBL1557907 | 0.77 | CTSD (0.49) | GPR119HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |