Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945931 | 0.85 | MAP4K3 (0.50) | SLC6A2SLC6A4SLC6A3MAP4K3SIGMAR1 | |
| SCHEMBL24265554 | 0.85 | MAP4K3 (0.48) | KDM1ASLC6A2SLC6A4SLC6A3GABRA1 | |
| SCHEMBL29946073 | 0.84 | MAP4K3 (0.49) | SLC6A2SLC6A4SLC6A3GABRA1GABRG2 | |
| SCHEMBL29946008 | 0.83 | INPPL1 (0.43) | KDM1AKCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29945912 | 0.82 | KDM1A (0.39) | KDM1AKCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29945962 | 0.79 | GPR119 (0.53) | — | |
| SCHEMBL29946021 | 0.77 | INPPL1 (0.43) | KDM1AMAP4K3SIGMAR1 | |
| SCHEMBL14635365 | 0.76 | SIGMAR1 (0.43) | SIGMAR1ALK | |
| SCHEMBL29946038 | 0.73 | KDM5A (0.45) | KDM1ASPHK2KCNH2SLC6A2SLC6A4 | |
| SCHEMBL29946013 | 0.72 | MAP4K3 (0.39) | MAP4K3SIGMAR1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |