Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24265551 | 0.91 | STS (0.48) | GPR119 | |
| SCHEMBL29946016 | 0.89 | GPR119 (0.46) | GPR119TP53 | |
| SCHEMBL29945962 | 0.86 | GPR119 (0.53) | GPR119TP53 | |
| SCHEMBL14636005 | 0.85 | GPR119 (0.50) | GPR119TP53 | |
| SCHEMBL29946022 | 0.81 | NR3C1 (0.44) | GPR119TP53 | |
| SCHEMBL29946041 | 0.80 | GPR119 (0.45) | GPR119TP53 | |
| SCHEMBL29945877 | 0.78 | GPR119 (0.43) | GPR119TP53 | |
| SCHEMBL1557907 | 0.78 | CTSD (0.49) | GPR119 | |
| SCHEMBL29946050 | 0.78 | GPR119 (0.50) | GPR119 | |
| SCHEMBL1582522 | 0.78 | GPR119 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |