SCHEMBL29946102

SCHEMBL29946102

Cc1ccc2occ(CN(C)CCN(C)Cc3cn(-c4ccccc4)c4ccccc34)c(=O)c2c1

nearest known ligand 0.82

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TNF P01375 6/20 0.82
TNFSF11 O14788 6/20 0.74
TNFRSF1A P19438 1/20 0.67
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.50
RAB9A P51151 1/20 0.47
PDE10A Q9Y233 6/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21162208 0.86 TNF (0.80) TNFTNFSF11TNFRSF1AALDH1A1TSHR
SCHEMBL29477172 0.81 TNF (1.00) TNFTNFSF11TNFRSF1A
SCHEMBL1270919 0.81 TNF (1.00) TNFTNFSF11TNFRSF1A
SCHEMBL30645540 0.81 TNF (1.00) TNFTNFSF11TNFRSF1A
SCHEMBL15159836 0.71 TNF (0.81) TNFTNFSF11TNFRSF1A
SCHEMBL15832298 0.70 TNF (0.78) TNFTNFSF11TNFRSF1A
SCHEMBL20975834 0.68 TNF (0.74) TNFTNFSF11TNFRSF1AALDH1A1
SCHEMBL11625434 0.67 MAOB (0.63) ALDH1A1TSHRRAB9APDE10A
SCHEMBL13296241 0.67 ALDH1A1 (0.66) ALDH1A1TSHRRAB9APDE10A
Hydrochloric Acid SCHEMBL4944672 0.67 TNFSF11 (0.59) TNFTNFSF11TNFRSF1AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 US disclosed
US-12171821-B2 Toxoplasma gondii vaccine WISCONSIN ALUMNI RESEARCH FOUNDATION (WARF) (US) 2024-12-24 US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 US disclosed
US-20240287574-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2024-08-29 US disclosed
EP-4397770-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PreAnalytiX GmbH (CH) 2024-07-10 EP disclosed
EP-3401406-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PREANALYTIX GMBH (CH) 2023-11-29 EP disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TNF 885/4885TNFSF11 942/4885TNFRSF1A 2247/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 TNF 885/4885TNFSF11 942/4885TNFRSF1A 2247/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TNF 885/4885TNFSF11 942/4885TNFRSF1A 2247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.