Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096908 | 0.76 | CYP3A4 (0.50) | BACE1ABL1ABCB1BCRKMT2A | |
| SCHEMBL5045304 | 0.75 | BACE1 (0.48) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL12648950 | 0.72 | PGR (0.48) | BACE1ABL1ABCB1BCRKMT2A | |
| SCHEMBL1119227 | 0.72 | ALDH1A1 (0.39) | KMT2ACYP3A4CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL12341703 | 0.71 | SQOR (0.55) | BACE1METAP2ABL1ABCB1BCR | |
| SCHEMBL26756579 | 0.71 | MAPT (0.44) | PDE4BPDE4APDE4CPDE4DABCB1 | |
| SCHEMBL10379922 | 0.71 | MAOA (0.50) | BACE1METAP2KMT2AALDH1A1KDM4E | |
| SCHEMBL12325398 | 0.70 | PDE4B (0.56) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28864507 | 0.70 | MAOA (0.46) | BACE1KMT2ACYP3A4CYP1A1CYP1A2 | |
| SCHEMBL24017198 | 0.70 | ABL1 (0.50) | BACE1METAP2ABL1ABCB1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115243765-A | Biphenyl compounds as SOCE modulators, compositions and uses thereof | 皮埃蒙特阿米阿伏伽德罗东方大学 | 2022-10-25 | — | — | CN | disclosed |