Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971322 | 0.93 | ALDH1A1 (0.56) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL13078874 | 0.78 | METAP2 (0.32) | ATMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2200076 | 0.77 | NPC1 (0.49) | ALDH1A1KDM4EMAPK1DYRK1ASMN1; SMN2 | |
| SCHEMBL8840880 | 0.75 | PDE4A (0.67) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL30601035 | 0.73 | KDM1A (0.43) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL12989702 | 0.72 | AKT1 (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL20848 | 0.72 | KMT2A (0.44) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL20699887 | 0.72 | PDE4A (0.53) | ALDH1A1KDM4EHPGDMAPK1PDE4A | |
| SCHEMBL23457543 | 0.71 | RPA1 (0.42) | ALDH1A1 | |
| SCHEMBL9356285 | 0.71 | KMT2A (0.42) | ALDH1A1KDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115243765-A | Biphenyl compounds as SOCE modulators, compositions and uses thereof | 皮埃蒙特阿米阿伏伽德罗东方大学 | 2022-10-25 | — | — | CN | disclosed |