Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.60 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24730459 | 1.00 | HSD17B1 (0.60) | HSD17B1HSD17B2LMNASMN1; SMN2NPC1 | |
| SCHEMBL24988088 | 0.76 | HTT (0.62) | HSD17B1HSD17B2LMNASMN1; SMN2NPC1 | |
| SCHEMBL24729349 | 0.75 | HSD17B10 (0.73) | HSD17B1HSD17B2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30192 | 0.75 | HSD17B1 (1.00) | HSD17B1HSD17B2LMNASMN1; SMN2NPC1 | |
| SCHEMBL29947652 | 0.75 | HSD17B10 (0.73) | HSD17B1HSD17B2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4746508 | 0.73 | NPC1 (0.54) | HSD17B1HSD17B2LMNASMN1; SMN2NPC1 | |
| SCHEMBL31056 | 0.72 | HSD17B1 (0.61) | HSD17B1HSD17B2LMNASMN1; SMN2NPC1 | |
| SCHEMBL479072 | 0.71 | TSHR (0.65) | LMNASMN1; SMN2RAB9ATP53KDM4E | |
| Hydrochloric Acid SCHEMBL31439010 | 0.70 | TSHR (0.63) | LMNASMN1; SMN2RAB9ATP53KDM4E | |
| Hydrochloric Acid SCHEMBL9190175 | 0.70 | TSHR (0.63) | LMNASMN1; SMN2RAB9ATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | claimed |
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |