SCHEMBL2994760

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2994755	1.00	ALOX5 (0.46)	ALOX5DYRK3PLAUMEN1KMT2A
	Trifluoroacetic Acid SCHEMBL4099206	0.96	ALOX5 (0.43)	ALOX5DYRK3PLAUMEN1KMT2A
	Trifluoroacetic Acid SCHEMBL4099194	0.96	ALOX5 (0.43)	ALOX5DYRK3PLAUMEN1KMT2A
	SCHEMBL4946166	0.91	DYRK3 (0.42)	DYRK3MEN1KMT2ACDK1PIK3CD
	SCHEMBL4947101	0.91	DYRK3 (0.42)	DYRK3MEN1KMT2ACDK1PIK3CD
	SCHEMBL4942268	0.89	ALDH1A1 (0.43)	DYRK3MEN1KMT2ACDK1PIK3CD
	SCHEMBL2993651	0.89	TSHR (0.42)	ALOX5DYRK3MEN1KMT2ACDK1
	SCHEMBL2993647	0.89	TSHR (0.42)	ALOX5DYRK3MEN1KMT2ACDK1
	SCHEMBL2989471	0.89	DYRK3 (0.47)	DYRK3MEN1KMT2ACDK1PIK3CD
	SCHEMBL2989478	0.89	DYRK3 (0.47)	DYRK3MEN1KMT2ACDK1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.