Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947798 | 0.87 | ADORA2A (0.40) | KDM4EMAPTADORA2AADORA1 | |
| SCHEMBL28522118 | 0.76 | RXRB (0.60) | RXRARXRBKDM4EGAAMAPT | |
| SCHEMBL2330196 | 0.68 | ADORA2A (0.76) | ADORA2AADORA1 | |
| SCHEMBL316288 | 0.68 | TSHR (0.50) | RXRARXRBKDM4EGAAMAPT | |
| SCHEMBL1655430 | 0.68 | GABRA1 (0.55) | RXRARXRBKDM4EGAAMAPT | |
| SCHEMBL24254767 | 0.68 | IKBKB (0.41) | RXRARXRBMAPTNOTUM | |
| SCHEMBL9962278 | 0.68 | POLB (0.41) | RXRARXRBMAPTPOLBTSHR | |
| SCHEMBL24795216 | 0.67 | DHODH (0.36) | RXRARXRBADORA2A | |
| SCHEMBL24795589 | 0.67 | DHODH (0.36) | RXRARXRB | |
| SCHEMBL23631404 | 0.67 | RXRA (0.38) | RXRARXRBNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |