SCHEMBL2994787

SCHEMBL2994787

C1CCC(CC2CCC3CC4CCCCC4C3C2)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.31
EPAS1 Q99814 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3002125 0.88
SCHEMBL10423624 0.87 HSD11B1 (0.34) HSD11B1
SCHEMBL26027382 0.79 ALOX5 (0.42)
SCHEMBL22137403 0.78 ALDH1A1 (0.47) HSD11B1
SCHEMBL6277727 0.75 ALDH1A1 (0.47) HSD11B1EPAS1
SCHEMBL30875827 0.75 HSD11B1 (0.43) HSD11B1EPAS1
SCHEMBL2994958 0.74 EPAS1 (0.30) EPAS1
Biphenyl SCHEMBL25346224 0.72 ALDH1A1 (0.53)
SCHEMBL1154960 0.72 ALDH1A1 (0.44) HSD11B1EPAS1
SCHEMBL6689602 0.72 ALDH1A1 (0.44) HSD11B1EPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed