Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | ATR | Q13535 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ATRIP | Q8WXE1 | 2/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21997022 | 1.00 | PIK3CA (0.45) | PIK3CAPIK3CBATRMAPTMEN1 | |
| SCHEMBL22014120 | 0.89 | MAP4K4 (0.45) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL21997840 | 0.85 | PIK3CA (0.52) | PIK3CAATRMAPTMEN1KMT2A | |
| SCHEMBL29947967 | 0.84 | ATR (0.51) | PIK3CAATRALDH1A1GAAATRIP | |
| SCHEMBL23946207 | 0.77 | ALDH1A1 (0.44) | PIK3CAPIK3CBMAPTMEN1KMT2A | |
| SCHEMBL24532867 | 0.76 | MAPT (0.58) | PIK3CAPIK3CBMAPTMEN1KMT2A | |
| SCHEMBL12701227 | 0.75 | PKM (0.57) | PIK3CAPIK3CBMAPTMEN1KMT2A | |
| SCHEMBL21997997 | 0.74 | PSMD14 (0.43) | ATRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29918750 | 0.74 | PSMD14 (0.43) | ATRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27144759 | 0.73 | MCHR1 (0.52) | PIK3CAPIK3CBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3886904-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4076536-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |