Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19240608 | 0.90 | PNMT (0.43) | PNMTTLR9TLR8TLR7PARP1 | |
| SCHEMBL23478610 | 0.80 | PNMT (0.39) | PNMT | |
| SCHEMBL13424003 | 0.79 | PNMT (0.61) | PNMT | |
| SCHEMBL6856723 | 0.78 | DAO (0.44) | HPGDALDH1A1POLBPKM | |
| SCHEMBL11977467 | 0.78 | HPGD (0.46) | HPGDALDH1A1POLBPKM | |
| SCHEMBL12563262 | 0.77 | PNMT (0.62) | PNMTTLR9TLR8TLR7PARP1 | |
| SCHEMBL3042471 | 0.77 | PNMT (0.44) | PNMTHPGD | |
| SCHEMBL11987732 | 0.77 | ALDH1A1 (0.49) | HPGDALDH1A1POLBPKM | |
| SCHEMBL11987742 | 0.77 | ALDH1A1 (0.49) | HPGDALDH1A1POLBPKM | |
| SCHEMBL23142133 | 0.75 | PNMT (0.39) | PNMTALDH1A1TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190772-A1 | Substituted Azepine Derivatives As Serotonin Receptor Modulators | BENNANI YOUSSEF L | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190772-A1 | Substituted Azepine Derivatives As Serotonin Receptor Modulators | HTR5A, HTR4, HTR2C | PNMT 70/4885HPGD 1617/4885ALDH1A1 789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.