Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | ECE1 | P42892 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 10/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630319 | 1.00 | CASP3 (0.41) | CASP3MMEACEECE1ERN1 | |
| SCHEMBL23630332 | 0.88 | ALDH1A1 (0.42) | CASP3MMEACEECE1ALDH1A1 | |
| SCHEMBL29948321 | 0.84 | CASP3 (0.43) | CASP3MMEACEECE1PKM | |
| SCHEMBL23630364 | 0.84 | CASP3 (0.43) | CASP3MMEACEECE1PKM | |
| SCHEMBL23630309 | 0.72 | KDM4E (0.39) | ERN1ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL29948225 | 0.72 | KDM4E (0.39) | ERN1ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL23630483 | 0.71 | KMT2A (0.50) | CASP3ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL23630363 | 0.71 | ALDH1A1 (0.44) | CASP3MMEACEECE1CCR4 | |
| SCHEMBL30225533 | 0.69 | KMT2A (0.46) | F2HTT | |
| SCHEMBL23630601 | 0.68 | CCR4 (0.40) | CASP3CCR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087651-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | claimed |
| EP-4087651-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | disclosed |