Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 14/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | ECE1 | P42892 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29948321 | 1.00 | CASP3 (0.43) | CASP3CCR4MMEACEECE1 | |
| SCHEMBL23630363 | 0.87 | ALDH1A1 (0.44) | CASP3CCR4MMEACEECE1 | |
| SCHEMBL29948277 | 0.84 | CASP3 (0.41) | CASP3CCR4MMEACEECE1 | |
| SCHEMBL23630319 | 0.84 | CASP3 (0.41) | CASP3CCR4MMEACEECE1 | |
| SCHEMBL29948271 | 0.79 | KMT2A (0.55) | — | |
| SCHEMBL23630459 | 0.79 | KMT2A (0.55) | — | |
| SCHEMBL29948257 | 0.77 | CCR4 (0.40) | CASP3CCR4LMNA | |
| SCHEMBL23630601 | 0.77 | CCR4 (0.40) | CASP3CCR4LMNA | |
| SCHEMBL25196437 | 0.76 | LMNA (0.57) | PKMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30225533 | 0.74 | KMT2A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021141506-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | claimed |
| WO-2021141506-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | disclosed |