Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 15/20 | 0.43 |
| ▸ | CA9 | Q16790 | 9/20 | 0.43 |
| ▸ | CA12 | O43570 | 8/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.42 |
| ▸ | CA5A | P35218 | 5/20 | 0.42 |
| ▸ | CA7 | P43166 | 5/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.42 |
| ▸ | CA6 | P23280 | 4/20 | 0.42 |
| ▸ | CA4 | P22748 | 4/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536020 | 0.83 | KIF11 (0.44) | KIF11TDP1ALDH1A1 | |
| SCHEMBL18007679 | 0.80 | CA2 (0.50) | CA2CA9CA12CA1CA5A | |
| SCHEMBL14655026 | 0.74 | KIF11 (0.49) | KIF11TSHRTDP1ALDH1A1 | |
| SCHEMBL20336329 | 0.73 | KIF11 (0.61) | KIF11 | |
| SCHEMBL11120807 | 0.72 | CA2 (0.45) | CA2CA9CA12CA1CA5A | |
| SCHEMBL2438979 | 0.70 | KIF11 (0.58) | KIF11CA2CA1TSHRTDP1 | |
| SCHEMBL13619662 | 0.70 | KIF11 (0.45) | KIF11CA2CA9CA1CA5A | |
| SCHEMBL22587365 | 0.70 | KIF11 (0.45) | KIF11 | |
| SCHEMBL4659933 | 0.70 | KIF11 (0.45) | KIF11 | |
| SCHEMBL20261725 | 0.70 | KIF11 (0.45) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |