SCHEMBL13619662

SCHEMBL13619662

Cc1ccc(C2(C(F)(F)F)N=N2)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.45
MAOB P27338 4/20 0.42
MAOA P21397 2/20 0.42
GABRA1 P14867 3/20 0.40
GABRB3 P28472 2/20 0.40
GABRG2 P18507 1/20 0.40
GABRB2 P47870 2/20 0.37
ACHE P22303 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
ADRA2A P08913 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30810730 0.94 KIF11 (0.53) KIF11MAOBMAOAGABRA1GABRB3
SCHEMBL20336329 0.81 KIF11 (0.61) KIF11GABRA1GABRB3GABRG2GABRB2
SCHEMBL15370170 0.78 KIF11 (0.42) KIF11MAOBMAOAGABRA1GABRB3
SCHEMBL23860299 0.77 KIF11 (0.45) KIF11GABRA1GABRB3GABRG2GABRB2
SCHEMBL20261725 0.77 KIF11 (0.45) KIF11GABRA1GABRB3GABRG2GABRB2
SCHEMBL6105719 0.77 KIF11 (0.49) KIF11GABRA1GABRB3GABRG2GABRB2
SCHEMBL14655026 0.77 KIF11 (0.49) KIF11GABRA1GABRB3GABRG2GABRB2
SCHEMBL4659933 0.77 KIF11 (0.45) KIF11GABRA1GABRB3GABRG2GABRB2
SCHEMBL22587365 0.77 KIF11 (0.45) KIF11MAOBMAOAGABRA1GABRB3
SCHEMBL18286628 0.77 KIF11 (0.53) KIF11GABRA1GABRB3GABRG2GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055246-A1 POLYMER FILMS, METHODS FOR PREPARING THEREOF, AND COMPOSITE CURRENT COLLECTORS THEREOF JIANGYIN NANOPORE INNOVATIVE MATERIALS TECHNOLOGY LTD. (CN) 2026-02-26 US disclosed
US-11913944-B2 Photoaffinity probes PROMEGA CORPORATION (US) 2024-02-27 US disclosed
US-11913944-B2 Photoaffinity probes PROMEGA CORPORATION (US) 2024-02-27 US disclosed
WO-2024037617-A1 POLYMER FILMS, METHODS FOR PREPARING THEREOF, AND COMPOSITE CURRENT COLLECTORS THEREOF JIANGYIN NANOPORE INNOVATIVE MATERIALS TECHNOLOGY LTD (CN) 2024-02-22 WO disclosed
WO-2023225336-A1 MET BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2023-11-23 WO disclosed
WO-2023215514-A2 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION (US) 2023-11-09 WO disclosed
US-11807623-B2 Nucleic acid-binding photoprobes and uses thereof ARRAKIS THERAPEUTICS, INC. (US) 2023-11-07 US disclosed
US-20230312520-A1 NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF ARRAKIS THERAPEUTICS, INC. 2023-10-05 US disclosed
US-20230176063-A1 PHOTOREACTIVE AND CLEAVABLE PROBES FOR TAGGING BIOMOLECULES ACADEMIA SINICA (TW) 2023-06-08 US disclosed
US-20220317138-A1 METHODS FOR DETERMINING THE CONCENTRATION OF A CARBAPENEM ANTIBIOTIC IN A BIOLOGICAL SAMPLE Université de Liège (BE) 2022-10-06 US disclosed
US-20170065726-A1 NOVEL CROSSLINKING REAGENTS, MACROMOLECULES, THERAPEUTIC BIOCONJUGATES, AND SYNTHETIC METHODS THEREOF CELLMOSAIC INC (US) 2017-03-09 US disclosed
US-9511150-B2 Crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof CellMosaic, Inc. (US) 2016-12-06 US disclosed
US-8907079-B2 Crosslinking reagents, macromolecules, therapeutic conjugates, and synthetic methods thereof CELLMOSAIC INC. (US) 2014-12-09 US disclosed
US-20140206903-A1 NOVELCROSSLINKING REAGENTS, MACROMOLECULES, THERAPEUTIC CONJUGATES, AND SYNTHETIC METHODS THEREOF CELLMOSAIC INC (US) 2014-07-24 US disclosed
WO-2012173575-A1 ALKYLAMINO BODIPY DYES AS SELECTIVE FLUORESCENT PROBES FOR PROTEINS AND MOUSE EMBRYONIC STEM CELLS NATIONAL UNIVERSITY OF SINGAPORE (SG) 2012-12-20 WO disclosed
EP-2116839-A1 Device for multiple ATR analysis Université Catholique de Louvain (BE) 2009-11-11 EP disclosed
US-20090130776-A1 BINDING PROTEIN MOLECULE CANON KABUSHIKI KAISHA (JP) 2009-05-21 US disclosed
US-20090130776-A1 BINDING PROTEIN MOLECULE CANON KABUSHIKI KAISHA (JP) 2009-05-21 US disclosed
US-20080072794-A1 Reactive Silicon Suboxide Flakes HOPPE HOLGER 2008-03-27 US disclosed
US-7176297-B2 Photoactivatable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2007-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312520-A1 NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF NSUN3, NSUN2, TARBP1 KIF11 4227/4885MAOB 1343/4885MAOA 2886/4885
US-20260055246-A1 POLYMER FILMS, METHODS FOR PREPARING THEREOF, AND COMPOSITE CURRENT COLLECTORS THEREOF TET2, PRPF40A, CFAP410 KIF11 2046/4885MAOB 1051/4885MAOA 316/4885
US-20170065726-A1 NOVEL CROSSLINKING REAGENTS, MACROMOLECULES, THERAPEUTIC BIOCONJUGATES, AND SYNTHETIC METHODS THEREOF CD44, ADH1C, EPCAM KIF11 370/4885MAOB 4316/4885MAOA 4481/4885
US-20090130776-A1 BINDING PROTEIN MOLECULE CD2BP2, HSPBP1, MYBBP1A KIF11 4287/4885MAOB 3741/4885MAOA 3430/4885
US-11807623-B2 Nucleic acid-binding photoprobes and uses thereof NSUN3, NSUN2, TARBP1 KIF11 4227/4885MAOB 1343/4885MAOA 2886/4885
US-20140206903-A1 NOVELCROSSLINKING REAGENTS, MACROMOLECULES, THERAPEUTIC CONJUGATES, AND SYNTHETIC METHODS THEREOF CD44, ADH1C, EPCAM KIF11 274/4885MAOB 4300/4885MAOA 4589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.