Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29948358 | 0.90 | TDP1 (0.30) | TDP1 | |
| SCHEMBL29931939 | 0.79 | MELK (0.33) | TDP1SMN1; SMN2 | |
| SCHEMBL29932016 | 0.78 | MCOLN2 (0.47) | — | |
| SCHEMBL23536010 | 0.73 | KDM1A (0.34) | — | |
| SCHEMBL28867476 | 0.71 | ALDH1A1 (0.42) | TDP1SMN1; SMN2 | |
| SCHEMBL29931901 | 0.69 | MCOLN2 (0.47) | — | |
| SCHEMBL29931763 | 0.69 | PAX8 (0.36) | SMN1; SMN2 | |
| SCHEMBL23536497 | 0.69 | PAX8 (0.36) | SMN1; SMN2 | |
| SCHEMBL29931911 | 0.68 | MCOLN2 (0.45) | — | |
| SCHEMBL29932104 | 0.66 | SMN1; SMN2 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |