Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.46 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CDC7 | O00311 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29949172 | 0.79 | CD44 (0.34) | HDAC4MEF2DCD44ELANEGAA | |
| SCHEMBL29949337 | 0.72 | EGFR (0.32) | CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL29949208 | 0.67 | BACE1 (0.35) | LMNAHSD17B10MAPTNPSR1 | |
| SCHEMBL2993419 | 0.66 | MAOA (0.45) | KDM4EALDH1A1TP53GAALMNA | |
| SCHEMBL9687484 | 0.64 | MAPT (0.44) | CD44KDM4EALDH1A1NPC1HSD17B10 | |
| SCHEMBL595335 | 0.61 | GABRA1 (0.48) | CD44ELANEKDM4EALDH1A1ALOX15 | |
| SCHEMBL31752918 | 0.61 | NOTUM (0.49) | NPC1 | |
| Dimethylamine SCHEMBL9706131 | 0.61 | GABRA1 (0.43) | CD44ELANEKDM4EALDH1A1GAA | |
| SCHEMBL1257763 | 0.61 | SLC6A4 (0.55) | CD44 | |
| SCHEMBL3132841 | 0.61 | CD44 (0.46) | CD44ALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11945811-B2 | Potassium channel inhibitors | ACESION PHARMA APS (DK) | 2024-04-02 | — | — | US | disclosed |
| CN-117561247-A | Novel potassium channel inhibitors | 阿塞西翁制药公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-4313973-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | Acesion Pharma ApS (DK) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022200162-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACECION PHARMA APS (DK) | 2022-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11945811-B2 | Potassium channel inhibitors | KCNJ2, KCNN2, KCNN1 | HDAC4 673/4885MEF2D 1382/4885CD44 4334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.