Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 5/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29949337 | 0.71 | EGFR (0.32) | MEN1KMT2A | |
| SCHEMBL2993419 | 0.68 | MAOA (0.45) | L3MBTL1ATMMEN1KMT2ALMNA | |
| SCHEMBL29949172 | 0.67 | CD44 (0.34) | ATMMEN1KMT2ALMNAMAPT | |
| SCHEMBL29949182 | 0.67 | HDAC4 (0.46) | LMNAMAPTNPSR1HSD17B10 | |
| SCHEMBL2719558 | 0.66 | GAPDH (0.57) | L3MBTL1MEN1KMT2AGAPDHLMNA | |
| SCHEMBL29463913 | 0.65 | MAPK10 (0.53) | BACE1MEN1KMT2ALMNAMAPT | |
| SCHEMBL19477810 | 0.65 | MAPK10 (0.53) | BACE1MEN1KMT2ALMNAMAPT | |
| SCHEMBL4826043 | 0.64 | — | — | |
| SCHEMBL5803747 | 0.64 | — | — | |
| SCHEMBL19930552 | 0.64 | NUDT1 (0.47) | L3MBTL1ATMGAPDHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561247-A | Novel potassium channel inhibitors | 阿塞西翁制药公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-4313973-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | Acesion Pharma ApS (DK) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022200162-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACECION PHARMA APS (DK) | 2022-09-29 | — | — | WO | disclosed |