Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29743218 | 0.71 | SLC6A4 (0.47) | SLC6A4KMT2ASLC6A2NOTUMNTSR1 | |
| SCHEMBL1967791 | 0.71 | SLC6A4 (0.47) | SLC6A4KMT2ASLC6A2NOTUMNTSR1 | |
| SCHEMBL30641461 | 0.70 | SLC6A2 (0.50) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3374081 | 0.70 | NOTUM (0.47) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14683431 | 0.70 | NOTUM (0.47) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL299494 | 0.70 | LMNA (0.50) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL299493 | 0.69 | SLC6A2 (0.42) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30952646 | 0.69 | KMT2A (0.47) | MAPK1CYP1A2CYP3A4CYP2C19SLC6A4 | |
| SCHEMBL24729036 | 0.68 | SLC6A2 (0.49) | SLC6A4SLC6A2 | |
| SCHEMBL599150 | 0.68 | SLC6A2 (0.49) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427170-A2 | ORGANIC COMPOUNDS HAVING COOLING PROPERTIES | Givaudan SA (CH) | 2012-03-14 | — | — | EP | claimed |