Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 4/20 | 0.43 |
| ▸ | CCND1 | P24385 | 4/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596619 | 0.71 | KMT2A (0.58) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL299492 | 0.70 | LMNA (0.41) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL18405592 | 0.70 | CDK4 (0.57) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13157277 | 0.70 | CDK4 (0.57) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL418336 | 0.70 | CDK4 (0.61) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL299235 | 0.68 | MAPK1 (0.68) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7349228 | 0.68 | LMNA (1.00) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL23844605 | 0.67 | LMNA (0.65) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10165541 | 0.67 | LMNA (0.65) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1519806 | 0.67 | KMT2A (0.71) | LMNAMAPK1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427170-A2 | ORGANIC COMPOUNDS HAVING COOLING PROPERTIES | Givaudan SA (CH) | 2012-03-14 | — | — | EP | claimed |