Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP1 | P07148 | 1/20 | 0.50 |
| ▸ | FABP6 | P51161 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25007409 | 0.82 | KDM4E (0.49) | NOS2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28971693 | 0.78 | CLK4 (0.52) | MEN1KMT2AKDM4EMAPTEGFR | |
| SCHEMBL30855014 | 0.77 | MTNR1A (0.53) | MEN1KMT2AALDH1A1KDM4EUSP2 | |
| SCHEMBL17186527 | 0.76 | HTT (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL30854998 | 0.75 | GAA (0.51) | MEN1KMT2AALDH1A1KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL17186249 | 0.75 | HTT (0.51) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL30438815 | 0.74 | PRMT6 (0.53) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL2719597 | 0.74 | TSHR (0.49) | MEN1KMT2AALDH1A1USP2CYP1A2 | |
| SCHEMBL30854991 | 0.74 | NPC1 (0.51) | ALDH1A1KDM4EMAPTTSHRKDR | |
| SCHEMBL30854968 | 0.74 | KDM4E (0.57) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007959-A1 | QUINOXALINE DERIVATIVES WHICH HAVE PARP INHIBITORY ACTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-30 | — | — | WO | disclosed |