SCHEMBL29950758

SCHEMBL29950758

O[C@]1(c2ccccc2)CCCC[C@@H]1Cc1cccnc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.45
CNR2 P34972 1/20 0.42
OPRM1 P35372 6/20 0.41
OPRL1 P41146 2/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
SLC6A9 P48067 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 1/20 0.41
PKM P14618 1/20 0.41
SLC6A2 P23975 4/20 0.40
SLC6A4 P31645 4/20 0.40
OPRD1 P41143 2/20 0.40
OPRK1 P41145 2/20 0.40
NPY1R P25929 1/20 0.40
HTT P42858 1/20 0.40
NPY2R P49146 1/20 0.40
ABL1 P00519 1/20 0.40
RIN1 Q13671 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28849444 1.00 TRPA1 (0.45) TRPA1CNR2OPRM1OPRL1MEN1
SCHEMBL28849419 0.85 TRPA1 (0.58) TRPA1CNR2OPRM1MEN1KMT2A
SCHEMBL5204638 0.78 OPRM1 (0.47) CNR2OPRM1OPRL1MEN1KMT2A
SCHEMBL5204648 0.78 CNR2 (0.41) CNR2OPRM1OPRL1MEN1KMT2A
Hydrochloric Acid SCHEMBL4864830 0.78 OPRM1 (0.47) CNR2OPRM1OPRL1MEN1KMT2A
Hydrochloric Acid SCHEMBL4864833 0.77 CNR2 (0.41) CNR2OPRM1OPRL1MEN1KMT2A
SCHEMBL28849438 0.76 MAPT (0.42) TRPA1CNR2OPRM1MEN1KMT2A
SCHEMBL5205111 0.74 SLC6A4 (0.64) OPRM1OPRL1MEN1KMT2ASLC6A9
SCHEMBL5206248 0.74 SLC22A1 (0.60) CNR2OPRM1OPRL1MEN1KMT2A
SCHEMBL898941 0.74 SLC6A2 (0.49) CNR2OPRM1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115108875-B Nitrogen-containing heteroarene chiral cyclic alcohol constructed by asymmetric catalysis of visible light, and preparation method and application thereof 河南师范大学 2023-07-04 CN disclosed
CN-115108875-A Nitrogen-containing heteroarene chiral cyclic alcohol constructed by visible light asymmetric catalysis, and preparation method and application thereof 河南师范大学 2022-09-27 CN disclosed