Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954098 | 0.81 | ERN1 (0.44) | ALDH1A1CTSLHSD17B10MAPTNPSR1 | |
| SCHEMBL29954118 | 0.80 | CHUK (0.35) | ALDH1A1HSD17B10KMT2AMEN1MAPT | |
| SCHEMBL29957701 | 0.79 | ALDH1A1 (0.37) | ALDH1A1GPR35KMT2AMEN1MAPT | |
| SCHEMBL29951646 | 0.78 | AR (0.34) | — | |
| SCHEMBL29952591 | 0.77 | MAPT (0.52) | ALDH1A1CTSLKMT2AMEN1MAPT | |
| SCHEMBL9061681 | 0.75 | ALDH1A1 (0.57) | ALDH1A1CAPN1CTSBCTSLCTSH | |
| SCHEMBL29950851 | 0.74 | MEN1 (0.34) | ALDH1A1HSD17B10KMT2AMEN1MAPT | |
| SCHEMBL29955079 | 0.73 | MEN1 (0.43) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL29954981 | 0.72 | AR (0.35) | — | |
| SCHEMBL29952812 | 0.72 | MAPT (0.52) | ALDH1A1CTSLKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |