Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | RB1 | P06400 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953493 | 0.82 | MAPT (0.41) | ALDH1A1MAPTSMN1; SMN2NPSR1MEN1 | |
| SCHEMBL29952812 | 0.79 | MAPT (0.52) | ALDH1A1MAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL29950813 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL29954098 | 0.78 | ERN1 (0.44) | ALDH1A1MAPTNPSR1TDP1 | |
| SCHEMBL29951956 | 0.77 | TRIM24 (0.41) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL29955402 | 0.74 | MAPT (0.44) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29954922 | 0.74 | DYRK1A (0.35) | ALDH1A1MAPTSMN1; SMN2NPSR1KMT2A | |
| SCHEMBL29952591 | 0.72 | MAPT (0.52) | ALDH1A1MAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL29951429 | 0.72 | APOL1 (0.33) | LMNASMN1; SMN2RAB9ANPC1TDP1 | |
| SCHEMBL15333338 | 0.72 | CYP19A1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |