Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RB1 | P06400 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952812 | 0.94 | MAPT (0.52) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL13191146 | 0.79 | CA12 (0.53) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL10173087 | 0.79 | CA12 (0.53) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29950813 | 0.77 | ALDH1A1 (0.39) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8506160 | 0.77 | CA12 (0.51) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL1121664 | 0.77 | MAPT (0.54) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29957067 | 0.77 | SIRT1 (0.45) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29957448 | 0.77 | CYP2D6 (0.42) | MAPTLMNAALDH1A1HTT | |
| SCHEMBL29958160 | 0.77 | MAPT (0.54) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29954098 | 0.74 | ERN1 (0.44) | MAPTALDH1A1NPSR1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |