Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.40 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5221782 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL4600422 | 0.87 | ERN1 (0.50) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL29955071 | 0.86 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL1398327 | 0.86 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL5621128 | 0.83 | ACLY (0.50) | ALDH1A1TSHRKDM4ELMNAERN1 | |
| SCHEMBL8327036 | 0.83 | CYP1A2 (0.40) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL4600063 | 0.83 | AR (0.43) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL26383587 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ETDP1TUBB1 | |
| SCHEMBL9699306 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ETDP1TUBB1 | |
| SCHEMBL16955355 | 0.82 | AR (0.47) | ALDH1A1KDM4EARDYRK1AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |