Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.40 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398327 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4ETDP1L3MBTL1 | |
| SCHEMBL29950818 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL5221782 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL2637060 | 0.84 | APP (0.51) | ALDH1A1TSHRKDM4ETDP1L3MBTL1 | |
| SCHEMBL2637062 | 0.84 | APP (0.51) | ALDH1A1TSHRKDM4ETDP1L3MBTL1 | |
| SCHEMBL27921460 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4ETDP1L3MBTL1 | |
| SCHEMBL21162204 | 0.82 | AR (0.47) | ALDH1A1ARGAKRIPK2COQ8A | |
| SCHEMBL18570516 | 0.82 | AR (0.54) | ALDH1A1ARERN1 | |
| SCHEMBL3699034 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ARLMNAHPGDCYP1A2 | |
| SCHEMBL11980116 | 0.78 | TRPV4 (0.39) | ALDH1A1L3MBTL1ARHPGDRAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026107227-A1 | COMPOSITIONS COMPRISING USP1 INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2026-05-21 | — | — | WO | disclosed |
| EP-4526302-A1 | PROCESS FOR THE PREPARATION OF FINERENONE AND INTERMEDIATES THEREOF | Alivus Life Sciences Limited (IN) | 2025-03-26 | — | — | EP | disclosed |
| EP-4511365-A1 | PROCESSES FOR THE PREPARATION OF FINERENONE | Teva Pharmaceuticals International GmbH (CH) | 2025-02-26 | — | — | EP | disclosed |
| CN-119219624-A | Dihydronaphthalene amide preparation method of class compound | 江苏吴中医药集团有限公司 | 2024-12-31 | — | — | CN | disclosed |
| WO-2024075139-A1 | A PROCESS FOR PREPARATION OF FINERENONE AND INTERMEDIATES THEREOF | MAITHRI DRUGS PRIVATE LIMITED (IN) | 2024-04-11 | — | — | WO | disclosed |
| EP-4286368-A1 | METHOD FOR THE PREPARATION OF 4-FORMYL-3-METHOXYBENZONITRILE | Bayer Aktiengesellschaft (DE) | 2023-12-06 | — | — | EP | disclosed |
| WO-2023223188-A1 | PROCESS FOR THE PREPARATION OF FINERENONE AND INTERMEDIATES THEREOF | GLENMARK LIFE SCIENCES LIMITED (IN) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023205164-A1 | PROCESSES FOR THE PREPARATION OF FINERENONE | TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) | 2023-10-26 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |