Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.40 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950818 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL4600422 | 0.87 | ERN1 (0.50) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL29955071 | 0.86 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL1398327 | 0.86 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL5621128 | 0.83 | ACLY (0.50) | ALDH1A1TSHRKDM4ELMNAERN1 | |
| SCHEMBL8327036 | 0.83 | CYP1A2 (0.40) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL4600063 | 0.83 | AR (0.43) | ALDH1A1TSHRKDM4ETDP1AR | |
| SCHEMBL26383587 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ETDP1TUBB1 | |
| SCHEMBL9699306 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ETDP1TUBB1 | |
| SCHEMBL16955355 | 0.82 | AR (0.47) | ALDH1A1KDM4EARDYRK1AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126771-A1 | PROCESS FOR PREPARING (Z)-3-(2-(5-BROMO-1H-INDOL-3-YL)-2-CYANOVINYL)-4-METHOXYBENZONITRILE | EVEXTA BIO (FR) | 2024-06-20 | — | — | WO | claimed |
| EP-4629988-A1 | DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER AND INFECTIONS | Centre National de la Recherche Scientifique (FR) | 2025-10-15 | — | — | EP | disclosed |
| CN-120112512-A | Process for the preparation of (Z) -3- (2- (5-bromo-1H-indol-3-yl) -2-cyanovinyl) -4-methoxybenzonitrile | 埃维克斯塔生物公司 | 2025-06-06 | — | — | CN | disclosed |
| WO-2024126771-A1 | PROCESS FOR PREPARING (Z)-3-(2-(5-BROMO-1H-INDOL-3-YL)-2-CYANOVINYL)-4-METHOXYBENZONITRILE | EVEXTA BIO (FR) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024126771-A1 | PROCESS FOR PREPARING (Z)-3-(2-(5-BROMO-1H-INDOL-3-YL)-2-CYANOVINYL)-4-METHOXYBENZONITRILE | EVEXTA BIO (FR) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024126771-A1 | PROCESS FOR PREPARING (Z)-3-(2-(5-BROMO-1H-INDOL-3-YL)-2-CYANOVINYL)-4-METHOXYBENZONITRILE | EVEXTA BIO (FR) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024121072-A1 | DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER AND INFECTIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-06-13 | — | — | WO | disclosed |
| CN-108341799-B | Novel indole derivatives for the treatment of cancer, viral infections and lung diseases | 生物控制术公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-113248448-A | 2-arylamine-4-amino quinazoline compound, preparation method and application thereof | 江苏正大丰海制药有限公司 | 2021-08-13 | — | — | CN | disclosed |
| US-10851054-B2 | Derivatives of indole for the treatment of cancer, viral infections and lung diseases | BIOKINESIS (FR) | 2020-12-01 | — | — | US | disclosed |
| US-20040082547-A1 | Novel compounds that inhibit factor xa activity | MORPHOCHEM (DE) | 2004-04-29 | — | — | US | disclosed |
| US-20040010011-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | SANOFI (FR) | 2004-01-15 | — | — | US | disclosed |
| EP-1370526-A1 | DIAMIDES WHICH INHIBIT TRYPTASE AND FACTOR XA ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2003-12-17 | — | — | EP | disclosed |
| EP-1315710-A1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002068390-A1 | DIAMIDES WHICH INHIBIT TRYPTASE AND FACTOR XA ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002016340-A1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-02-28 | — | — | WO | disclosed |
| US-5716971-A | FOR TREATMENT OF ANGINA PECTORIS AND HYPERTENSION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0623597-B1 | Pyridine derivatives, with potassium channel opening activity | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-22 | — | — | EP | disclosed |
| EP-0623597-A1 | Pyridine derivatives, with potassium channel opening activity | Takeda Chemical Industries, Ltd. (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-4598077-A | Amidine derivatives and cardiotonic compositions | TORII & CO. LTD. (JP) | 1986-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010011-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | ABAT, TNNT2, BCAT1 | ALDH1A1 129/4885TSHR 4555/4885KDM4E 947/4885 |
| US-20040082547-A1 | Novel compounds that inhibit factor xa activity | F11, TFPI, SERPINC1 | ALDH1A1 1604/4885TSHR 2698/4885KDM4E 3433/4885 |
| US-10851054-B2 | Derivatives of indole for the treatment of cancer, viral infections and lung diseases | IDO2, IDO1, ING2 | ALDH1A1 2533/4885TSHR 4322/4885KDM4E 1237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.