Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 3/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950835 | 0.88 | KMO (0.42) | PDE4APDE4BPDE4CPDE4DKMO | |
| SCHEMBL29951510 | 0.83 | KAT2B (0.42) | PDE4APDE4BPDE4CPDE4DRORC | |
| SCHEMBL29952374 | 0.80 | MCHR1 (0.44) | SCDKMORORCMCHR1 | |
| SCHEMBL29953999 | 0.76 | CSNK2A1 (0.36) | SCDMCHR1 | |
| SCHEMBL29954305 | 0.75 | PARP10 (0.39) | PDE4APDE4BPDE4CPDE4DPARP10 | |
| SCHEMBL29952825 | 0.74 | MKNK1 (0.38) | PDE4APDE4BPDE4CPDE4DPARP10 | |
| SCHEMBL29956096 | 0.73 | POLB (0.35) | PDE4DSCDRORCACACBMCHR1 | |
| SCHEMBL29955972 | 0.72 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DPARP10 | |
| SCHEMBL29953293 | 0.71 | MAP4K4 (0.42) | PDE4APDE4BPDE4CPDE4DPARP10 | |
| SCHEMBL29956632 | 0.70 | ALDH1A1 (0.43) | PDE4APDE4BPDE4CPDE4DPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |