Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643134 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10RIPK1CA1 | |
| SCHEMBL29951079 | 0.78 | HSD17B3 (0.39) | HSD17B3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL9212931 | 0.75 | HSD17B3 (0.47) | HSD17B3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29951374 | 0.75 | HDAC3 (0.44) | HSD17B3NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL257905 | 0.74 | CRHBP (0.53) | ALDH1A1CA1CA2NR1H2NR1H3 | |
| SCHEMBL29955063 | 0.73 | LIPG (0.44) | HSD17B3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL17485375 | 0.72 | LPL (0.47) | RIPK1CA1CA2 | |
| SCHEMBL29952570 | 0.71 | NR1H2 (0.54) | ALDH1A1CA1CA2NR1H2NR1H3 | |
| SCHEMBL16576649 | 0.71 | LPL (0.34) | KDM4EALDH1A1RIPK1CA1CA2 | |
| SCHEMBL257893 | 0.71 | HSD17B3 (0.41) | HSD17B3KDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |