Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13738402 | 0.86 | RXRA (0.42) | LIPGHPGDMEN1KMT2A | |
| SCHEMBL29955523 | 0.84 | RECQL (0.41) | LIPGKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL13737929 | 0.82 | PPARA (0.47) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29951079 | 0.80 | HSD17B3 (0.39) | HSD17B3TAAR1NR1H2NR1H3KDM4E | |
| SCHEMBL4537 | 0.80 | LIPG (0.50) | LIPGKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL29504654 | 0.80 | LIPG (0.50) | LIPGKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL257893 | 0.80 | HSD17B3 (0.41) | HSD17B3TAAR1CRHBPCRHR2NR1H2 | |
| SCHEMBL15780772 | 0.79 | ALDH1A1 (0.44) | CA12CA2CA9KDM4EALDH1A1 | |
| SCHEMBL29950775 | 0.79 | TSHR (0.55) | LIPGTAAR1NR1H2NR1H3KDM4E | |
| SCHEMBL14753645 | 0.77 | LIPG (0.47) | LIPGKDM4EALDH1A1LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |