Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953905 | 0.91 | L3MBTL1 (0.54) | LMNATSHRESR1TDP1HPGD | |
| SCHEMBL878699 | 0.91 | L3MBTL1 (0.54) | LMNATSHRESR1TDP1HPGD | |
| SCHEMBL5568364 | 0.90 | LMNA (0.53) | LMNAALDH1A1TSHRESR1TDP1 | |
| SCHEMBL361141 | 0.87 | CYP4F2 (0.54) | LMNAALDH1A1TSHRESR1KDM4E | |
| SCHEMBL111664 | 0.85 | LMNA (0.75) | LMNAALDH1A1TSHRESR1CHRM1 | |
| SCHEMBL4214601 | 0.84 | SERPINE1 (0.43) | LMNAALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL522694 | 0.81 | LMNA (0.64) | LMNAALDH1A1TSHRESR1CHRM1 | |
| SCHEMBL5165716 | 0.80 | LMNA (0.68) | LMNAALDH1A1TSHRESR1CHRM1 | |
| SCHEMBL18541492 | 0.80 | ALDH1A1 (0.66) | LMNAALDH1A1TSHRESR1CHRM1 | |
| SCHEMBL1586281 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRJMJD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |