Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27430945 | 0.93 | LMNA (0.55) | LMNAALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL7471305 | 0.91 | LMNA (0.54) | LMNAALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL8759408 | 0.90 | L3MBTL1 (0.56) | LMNATDP1ESR1TSHRNPC1 | |
| SCHEMBL111664 | 0.88 | LMNA (0.75) | LMNAALDH1A1TDP1ESR1CHRM1 | |
| SCHEMBL641903 | 0.86 | POLB (0.62) | LMNAALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL31237097 | 0.86 | POLB (0.62) | LMNAALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL11354226 | 0.83 | CES2 (0.52) | LMNAALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL28953541 | 0.83 | CES2 (0.52) | LMNAALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL5165716 | 0.83 | LMNA (0.68) | LMNAALDH1A1TDP1ESR1CHRM1 | |
| SCHEMBL6057202 | 0.81 | LMNA (0.66) | LMNAALDH1A1TDP1ESR1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647615-B1 | Process for the preparation of 5-fluoroanthranilic acid alkyl esters and or 5-fluoroanthranilic acid | HOECHST AG (DE) | 1997-05-28 | — | — | EP | claimed |
| US-5543550-A | NITRATING ALKYL ESTER OF 3-FLUOROBENZOIC ACID DISSOLVED IN SOLVENT-FREE SULFURIC ACID, THEN ADDING WATER, SEPARATION, HYDROLYSIS, PRESSURIZED CATALYTIC HYDROGENATION OF THE NITRATED ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-06 | — | — | US | claimed |
| CN-102365255-B | Method for producing alcohol compound and catalyst therefor | SUMITOMO CHEMICAL CO | 2015-01-07 | — | — | CN | disclosed |
| CN-102365254-B | Method for producing alcohol compound | SUMITOMO CHEMICAL CO | 2014-08-27 | — | — | CN | disclosed |
| CN-102365255-A | Method for producing alcohol compound and catalyst therefor | SUMITOMO CHEMICAL CO | 2012-02-29 | — | — | CN | disclosed |
| CN-102365254-A | Method for producing alcohol compound | SUMITOMO CHEMICAL CO | 2012-02-29 | — | — | CN | disclosed |
| EP-2415742-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR | Sumitomo Chemical Company, Limited (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120029195-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20120010417-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-12 | — | — | US | disclosed |
| US-5543550-A | NITRATING ALKYL ESTER OF 3-FLUOROBENZOIC ACID DISSOLVED IN SOLVENT-FREE SULFURIC ACID, THEN ADDING WATER, SEPARATION, HYDROLYSIS, PRESSURIZED CATALYTIC HYDROGENATION OF THE NITRATED ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010417-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | ADH1A, ADH1C, ADH5 | LMNA 3279/4885ALDH1A1 18/4885ADRB2 1429/4885 |
| US-20120029195-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR | ADH1A, ADH1C, ADH5 | LMNA 4306/4885ALDH1A1 33/4885ADRB2 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.