Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.43 |
| ▸ | DRD4 | P21917 | 5/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553727 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4ESIGMAR1HTT | |
| SCHEMBL15330514 | 0.80 | LTA4H (0.49) | ALDH1A1KDM4ELTA4HOPRM1OPRK1 | |
| SCHEMBL29954738 | 0.80 | ALDH1A1 (0.68) | ALDH1A1POLBKDM4EHTT | |
| SCHEMBL2556300 | 0.79 | ALDH1A1 (0.51) | ALDH1A1POLBKDM4EHTT | |
| SCHEMBL30334846 | 0.77 | GRM2 (0.48) | ALDH1A1POLBKDM4ESIGMAR1DRD4 | |
| SCHEMBL20605142 | 0.77 | HRH3 (0.51) | ALDH1A1HTT | |
| SCHEMBL29952220 | 0.76 | ADRB2 (0.46) | ALDH1A1POLBKDM4EHTTMCHR1 | |
| SCHEMBL791901 | 0.76 | MEN1 (0.55) | ALDH1A1KDM4ESIGMAR1LTA4HOPRM1 | |
| SCHEMBL2561782 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHTTLTA4HCCR3 | |
| SCHEMBL2561401 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |