Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 4/20 | 0.34 |
| ▸ | GSK3B | P49841 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955023 | 0.83 | KMT2A (0.49) | MEN1KMT2AALDH1A1TDP1LMNA | |
| SCHEMBL29954953 | 0.74 | KDM4E (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28165405 | 0.74 | KMT2A (0.53) | MEN1KMT2AALDH1A1TDP1LMNA | |
| SCHEMBL2343158 | 0.74 | KDM4E (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1144571 | 0.69 | MAT2A (0.51) | MEN1KMT2ALMNA | |
| SCHEMBL11282910 | 0.69 | KMT2A (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2GSK3A | |
| SCHEMBL1150448 | 0.68 | REN (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1150009 | 0.68 | FEN1 (0.52) | MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL1150001 | 0.68 | REN (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL29956626 | 0.68 | MEN1 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |