Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950876 | 0.83 | MEN1 (0.50) | KMT2AMEN1ALDH1A1TDP1GSK3A | |
| SCHEMBL29954953 | 0.81 | KDM4E (0.52) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL2343158 | 0.81 | KDM4E (0.52) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL1144571 | 0.76 | MAT2A (0.51) | KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL1150001 | 0.75 | REN (0.39) | KMT2AMEN1ALDH1A1NPSR1KDM4E | |
| SCHEMBL1150448 | 0.75 | REN (0.39) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL1150009 | 0.75 | FEN1 (0.52) | KMT2AMEN1ALDH1A1MAPK1KDM4E | |
| SCHEMBL1150349 | 0.74 | REN (0.40) | KMT2AMEN1ALDH1A1ATMKDM4E | |
| SCHEMBL1149900 | 0.74 | REN (0.40) | KMT2AMEN1ALDH1A1GSK3B | |
| SCHEMBL2349748 | 0.74 | KMT2A (0.39) | KMT2AMEN1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |